Do you have hard to control blood pressure and have not had success finding the right drug? Do you have anxiety and are scared to try new medications? Are you confident your child needs medication to help them focus but do not want to waste time finding the right medication?
If so, you are not alone. Most people would prefer to find the right medication at the first time. With experience a good family doctor can get it right on average by the second time.
We have been studying the research for pharmacogenomics for over 10 years and have not been ready to introduce it to our patients until now.
We are confident that there is enough research out there that can properly point us in a direction that shows which enzymes work best with the respective medication. This research is called pharmacogenomics and is only getting better over time.
We have just started offering this to our patients and we will be able to help them understand which medications will work best on their body.
The test is a blood test and it will stay in a database that can be used in the future as more data is obtained on each drug and genome.
What this means is we can tell you which statin drug would have the best probability of working in your body and which ones are more likely to cause side effects.
If you are interested, please ask your PrimeCare physician about this test. Not all insurances will pay for this testing, however, the cost may be just the same as multiple visits to get a specific medication that works for you.
The list of drugs we can test will grow over time and the information will continue to help us be more exact. The following pharmacogenomics panels will be available for you at our Wixom office:
Antiplatelet Agents – Aspirin, Cilostazol, Clopidogrel, Prasugrel, Ticagrelor
Statins -Atorvastatin, Fluvastatin, Lovastatin,Pitavastatin,Pravastatin, Rosuvastatin, Simvastatin
Anticlotting Agents – Acenocoumarol,Coumarol,Fluindione,Phenprocoumon, Warfarin
Thrombophilia – Susceptibility to Factor II, Factor V Leiden
Calcium Channel Blockers – Amlodipine, Nifedipine
Beta Blockers – Bufuralol,Carvedilol,Metoprolol,Propranalol,Talinolol,Timolol
Congestive Heart Failure – Digoxin
Antiarrhythmics – Flecainide, Propafenone
Antihypertensives – Benazepril, Debrisoquine, Enalapril, Irbesartan, Losartan,
Addiction to Alcohol, Cocaine, Heroin, Opioids, Tobacco – Bupropion, Disulfiram, Levodopa,Methadone,Naloxone,Naltrexone, Nicotine
ADHD-Atomoxetine, Dextroamphetamine, Methylphenidate
Alzheimer’s Disease – Donepezil, Galantamine, Olanzapine, Risperidone
Anxiety, Insomnia, Severe Agitation-Dexmedetomidine, Escitalopram, Lorazepam, Midazolam, Oxazepam, Venlafaxine
Autism Spectrum Disorders – Quetiapine, Risperidone
Bipolar Disorder – Lithium, Olanzapine, Quetiapine
Depressive Disorder and Major Depressive Disorder-Agomelatine,Amitriptyline, Antipsychotics (gen), Citalopram, Clomipramine, Desipramine, Diazepam, Doxepin, Escitalopram, Fluoexitine, Fluvoxamine, Imipramine, Maprotiline, Milnacipran, Mirtazapine, Nortriptyline, Olanzapine,Opipramol, Paroxetine,Quetiapine, Sertraline, SSRIs (gen),Trimipramine, Venlafaxine, Vortioxetine
Epilepsy -Antiepileptics (gen),Carbamazepine,Clobazam, Lamotrigine, Mephenytoin, Phenobarbital, Phenytoin, Valproic acid
Parkinson’s Disease – Entacaptone
Schizophrenia – Antipsychotics (gen), Aripiprazole, Chlorpromazine, Clozapine, Fluphenazine, Haloperidol, Iloperidone, Nemonapride, Olanzapine, Quetiapine, Risperidone, Thioridazine, Trifluoperazine, Zuclopenthixol
Transplantation – Busulfan, Cyclophosphamide, Cyclosporine, Everolimus, Methylprednisone, Prednisone/Prednisolone, Sirolimus, Tacrolimus
Rheumatoid Arthritis – Leflunomide, Methotrexate, Sulfasalazine
Type-II Diabetes – Repaglinide, Sulfoureas (gen), Urea Derivatives (gen)
Gastritis and Colitis – Esomeprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole, Tacrolimus
Inflammation – Celecoxib, Dexamethasone, Diclofenac, Flurbiprofen, Lornoxicam, Prednisone/Prednisolone
Systemic Lupus Erythematosus-Cyclophosphamide
Gout – Allopurinol
Antihistamines – Fexofenadine
Antiasthmatics – Zafirlukast
HIV/AIDS-Atazanavir, Efavirenz, Etravirine, Indinavir, Lamivudine, Lopinavir,Nelfinavir, Nevirapine, Ritonavir, Zidovudine
Antifungals and Antibiotics – Daptomycin, Dicloxacillin, Erythromycin, Rifampicin, Sulfonamides (gen), Voriconazole
Pain Management – General – Alfentanil, Codeine, Fentanyl, Hydrocodone, Ketamine, Methadone, Morphine,Opioids (gen), Oxycodone,Sumatriptan,Tramadol
Sedatives and Relaxants, including muscle relaxants – Carisoprodol, Midazolam, Propofol, Rocuronium, Tolperisone
Alkaloids – Vincristine
Alkylating Agents-Cyclophosphamide, Dacacarbazine
Antimetabolites – Cytarabine, Fludarabine, Mercaptopurine, Methotrexate, Silibinin
Anthracyclines-Anthracyclines (gen), Doxorubicin, Epirubicin, Idarubicin
Kinase Inhibitors – Gefitinib, Icotinib, Imatinib, Sorafenib, Sunitinib
Platinum Derivatives -Carboplatin,Cisplatin,Oxaliplatin,Platinum Compounds (gen)
Steroid Hormone Inhibitors – Mitotane, Tamoxifen,Taxanes – Docetaxel, Paclitaxel, Taxanes (gen)
Topoisomerase Inhibitors – Etoposide, Irinotecan
Uracil Derivatives – Capecitabine, Fluorouracil, Folfox, Folox, Leucovorin, Tegafur, Xelox
Antiemetics – Dolasetron,Granisetron,Ondansetron
Anesthesiology – Nitrous Oxide
Beta Thalassemia – Deferasirox
Narcolepsy – Modafinil
Contraception – Oral Contraceptives (gen)
Erectile Dysfunction – Vardenafil
Bladder Control – Tolterodine